The best benzoyl peroxide products, according to dermatologists (2024)

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Chances are you’ve seen cleansers and body washes made with benzoyl peroxide while shopping for skin care products — after all, it’s one of the most popular ingredients for treating acne-prone skin. If you’re dealing with stubborn blackheads or a mild breakout, I spoke to board-certified dermatologists about how benzoyl peroxide can help to heal your skin and rounded up their product recommendations for you to shop.

SKIP AHEAD What is benzoyl peroxide? | How I picked the best benzoyl peroxide products | The best benzoyl peroxide products | How to shop for benzoyl peroxide products

What is benzoyl peroxide?

Benzoyl peroxide is an over the counter, FDA-approved active ingredient used primarily for the treatment of acne, according to board-certified dermatologist Dr. Marguerite Germain. This ingredient is bactericidal, meaning it can directly kill the bacteria most commonly involved in acne (Cutibacterium acnes). It is also sebostatic, which means it can help reduce oil production, and keratolytic, which means it can help remove dead skin cells that clog pores, according to Sadeghpour. It’s also especially great because C. acnes doesn’t build a tolerance to benzoyl peroxide as it would with other active antibiotic treatments, says Germain.

On the other hand, it can be irritating, causing dryness, redness, and scaling, especially for those with sensitive skin. This is usually overcome by using a lower strength, decreasing the frequency of use, or using it short term and returning to another treatment, says Germain. A moisturizer often will remedy much of the issue, she says. In addition to its drying and irritating side effects, it can also have bleaching qualities, causing it to discolor colored fabrics and towels, says Sadeghpour.

How I picked the best benzoyl peroxide products

Experts recommend considering the following when shopping for a skin care product with benzoyl peroxide as its main ingredient:

  • Formulation: Benzoyl peroxide can be found in different formulations, including cleansers, body washes, gels, spot treatments and more. In general, the longer a chemical ingredient stays in contact with the skin, the more potent its effect can be — for example, cleansers are rinsed off quickly while spot treatments dry and stay on the skin. But the longer it stays on your skin, the higher the risk for irritation, says Dr. Mona Sadeghpour. More on how to approach formulations below.

  • Additional ingredients: Since benzoyl peroxide can be drying, it should be combined with hydrating and soothing ingredients in a product to help prevent any potential irritation. This includes hyaluronic acid, glycerin, ceramides and niacinamide, according to our experts.

  • Concentration: The strength of your over-the-counter benzoyl peroxide will range from 2.5% to 10%. The strength you use will depend on your skin type and its tolerance. For example, if you have sensitive or dry skin, you may want to use a product with a smaller concentration to avoid irritation and excessive dryness, according to our experts. Also, if you’re introducing this ingredient to your skin, consider starting with the lowest amount at first, says Germain.

  • Price: My roundup includes products as low as $10 and as high as $56.

The best benzoyl peroxide in 2024

Listed below are expert-recommended benzoyl peroxide products that can help treat facial and body acne. I also included highly rated options that align with the dermatologists’ guidance.

Best facial cleanser: Cerave Acne Foaming Cream Cleanser

Cerave Acne Foaming Cream Cleanser

The best benzoyl peroxide products, according to dermatologists (1)

  • Cerave Acne Foaming Cream Cleanser $ at Amazon

  • Cerave Acne Foaming Cream Cleanser $ at Target

  • Cerave Acne Foaming Cream Cleanser $ at Ulta

This cleanser’s 4% benzoyl peroxide formulation is high enough to pack an acne punch and is combined with ceramides, niacinamide, and hyaluronic acid to help calm the skin and retain moisture, according to Sadeghpour.

Best for cystic acne: Paula’s Choice Regular Strength Daily Skin Clearing Treatment

Paula's Choice Regular Strength Daily Skin Clearing Treatment

  • Paula's Choice Regular Strength Daily Skin Clearing Treatment $ at Amazon

  • Paula's Choice Regular Strength Daily Skin Clearing Treatment $ at Sephora

  • Paula's Choice Regular Strength Daily Skin Clearing Treatment $ at Dermstore

If you have cystic acne or mild to moderate acne, consider using this lightweight lotion, which has a 4.6-star average rating from over 2,900 reviews on Amazon. Aside from helping to control oil and breakouts, this treatment has bisabolol and allantoin to help soothe the skin and reduce redness, according to the brand. For the best results, apply the matte-finish lotion to your skin after cleansing twice daily.

Best body wash: PanOxyl 10% Benzoyl Peroxide Body Wash

PanOxyl 10% Benzoyl Peroxide Body Wash

The best benzoyl peroxide products, according to dermatologists (3)

  • PanOxyl 10% Benzoyl Peroxide Body Wash $ at Amazon

  • PanOxyl 10% Benzoyl Peroxide Body Wash $ at Walmart

  • PanOxyl 10% Benzoyl Peroxide Body Wash $ at Target

This drugstore body wash is an effective treatment for body acne or folliculitis (inflammation of hair follicles) because of its high concentration of benzoyl peroxide, according to Sadeghpour. It’s available in two strengths, so you can choose which one would be best for the severity of your acne and your skin’s tolerance level, she says.

Best for skin barrier health: Kate Somerville Anti Bac Acne Clearing Lotion

Kate Somerville Anti Bac Acne Clearing Lotion

The best benzoyl peroxide products, according to dermatologists (4)

You can use this lotion as a spot treatment on pimples and blackheads up to three times a day in order to help minimize the appearance of pores and reduce oil, according to the brand. Reviewers say that even their sensitive skin can tolerate it, and there is a noticeable difference within a few days of applying it regularly. They also say it can be quite drying, so be sure to follow it up with a moisturizer. This treatment has a 4.5-star average rating from over 600 reviews at Sephora.

Best for moisturizing: Cetaphil Gentle Clear Complexion-Clearing BPO Acne Cleanser

Cetaphil Gentle Clear Complexion-Clearing BPO Acne Cleanser

The best benzoyl peroxide products, according to dermatologists (5)

  • Cetaphil Gentle Clear Complexion-Clearing BPO Acne Cleanser $ at Amazon

  • Cetaphil Gentle Clear Complexion-Clearing BPO Acne Cleanser $ at Target

  • Cetaphil Gentle Clear Complexion-Clearing BPO Acne Cleanser $ at Walmart

Aside from being formulated to clear acne within one week of consistent use, this creamy cleanser also hydrates and soothes the skin with the help of glycerin and licorice root. The licorice root also helps reduce any redness linked directly with acne, according to the brand. Reviewers say that while it’s an effective treatment and reduces irritation, it does have a slight scent that isn’t masked by artificial fragrances.

Best spot treatment: La Roche-Posay Effaclar Duo Acne Spot Treatment

La Roche-Posay Effaclar Duo Acne Spot Treatment

The best benzoyl peroxide products, according to dermatologists (6)

  • La Roche-Posay Effaclar Duo Acne Spot Treatment $ at Amazon

  • La Roche-Posay Effaclar Duo Acne Spot Treatment $ at Ulta

  • La Roche-Posay Effaclar Duo Acne Spot Treatment $ at Target

This spot treatment comes recommended by Sadeghpour because it has a combination of micronized BPO and lipo-hydroxy acid (a derivative of salicylic acid). This allows for deeper penetration and skin exfoliation while glycerin in the formula allows for hydration and better tolerability, she says. Add a thin layer of the lightweight lotion to the affected area one to three times a day, says the brand.

Best soothing treatment: Avène Cleanance Acne Medicated Clearing Treatment

Avène Cleanance Acne Medicated Clearing Treatment

The best benzoyl peroxide products, according to dermatologists (7)

  • Avène Cleanance Acne Medicated Clearing Treatment $ at Ulta

  • Avène Cleanance Acne Medicated Clearing Treatment $ at Target

  • Avène Cleanance Acne Medicated Clearing Treatment $ at Avene

This cleanser is non-irritating because it has soothing and calming thermal spring water to counteract any irritation that benzoyl peroxide might cause, according to the brand.

How to shop for benzoyl peroxide products

Using a product with benzoyl peroxide can be a great first step to preventing and treating acne. Below are factors our experts recommend considering when shopping for one. Some factors can be based on personal preference, while others may benefit from a discussion with a board-certified dermatologist.

Formulation

Benzoyl peroxide is available in different formulations, including gels, cleansers, masks, spot treatments and lotions. The option you choose will depend on your preference, whether you want to target a large or small area, and whether you want a leave-on or rinse-off treatment, says Germain.

Cleansers and body washes: Cleansers (especially those with lower concentrations of BPO) are “easier” on the skin because they can be quickly washed off, says Sadeghpour. They also provide wide protection from new breakouts and control oil over the whole area to which they are applied, according to Germain. Dermatologists frequently recommend BPO washes as part of a multimodal treatment plan for managing acne.

Masks and lotions: Masks and lotions stay in contact with the skin longer and can be great for combatting acne and covering a large surface. This formulation may be appropriate for someone with oily skin. Those with sensitive skin may have a harder time tolerating these, says Sadeghpour.

Spot treatments: Using a spot treatment (whether it’s in gel or lotion form) is the best way to test how your skin reacts to BPO.These allow you to target the acne lesion itself without exposing the surrounding skin to potential irritation, she says. If you use a gel spot treatment, use it sparingly and rub it in well — if you see white spots, you are using way too much, says Germain.

Concentration

When shopping for a skin care product with benzoyl peroxide, you’ll notice it has different percentages, including 2.5%, 5% and 10%. It’s important to remember the following when deciding which level of concentration is best for you.

Affected area. Different parts of the body may vary in how well they can tolerate lower or higher percentages. For example, even those with sensitive skin may be able to tolerate a higher percentage of BPO for body acne because the skin in those areas (back, chest, extremities) is thicker, whereas they may need to stick to lower percentages for treating acne on their face and neck where skin is thinner. A board-certified dermatologist can help you select the ideal percentage based on your skin type.

Higher is not always better. According to studies, lower percentages, such as 2.5%, can be just as effective as higher percentages without the added higher risk of irritation that comes with higher percentages, says Sadeghpour.

Additional ingredients

Many times, benzoyl peroxide is formulated with other ingredients to balance out any dryness and irritation that can commonly occur. Some soothing and hydrating ingredients include hyaluronic acid, niacinamide, ceramides and glycerin.

There are also ingredients you don’t want to use in conjunction with benzoyl peroxide. This includes retinoids since it will make them less effective by degrading them, according to Germain. However, there are current studies being conducted that are showing BPO and tretinoin degradation not occurring when there is an optimized formula, says Sadeghpour. When in doubt, consult a board-certified dermatologist to determine whether or not you can mix certain skin care products together as part of your treatment plan.

Also, the antibiotic medication dapsone (also known as aczone) and hydroquinone (a topical bleaching cream) can cause skin discoloration when combined with BPO at the same time, according to Sadeghpour.

Meet our experts

At NBC Select, we work with experts who have specialized knowledge and authority based on relevant training and/or experience. We also take steps to ensure all expert advice and recommendations are made independently and without undisclosed financial conflicts of interest.

Why trust NBC Select?

Bianca Alvarez is an associate reporter and has been covering beauty, including the best exfoliating products and retinol alternatives. For this piece, she interviewed dermatologists about the benefits and drawbacks of benzoyl peroxide. She also compiled a list of product recommendations based on their guidance.

Catch up on NBC Select’s in-depth coverage of personal finance, tech and tools, wellness and more, and follow us on Facebook, Instagram, Twitter and TikTok to stay up to date.

The best benzoyl peroxide products, according to dermatologists (2024)

FAQs

The best benzoyl peroxide products, according to dermatologists? ›

Combination acne medications that your dermatologist may prescribe include: Retinoid + benzoyl peroxide (Brand names: Epiduo, Epiduo Forte, Twyneo)

Can a dermatologist prescribe benzoyl peroxide? ›

Combination acne medications that your dermatologist may prescribe include: Retinoid + benzoyl peroxide (Brand names: Epiduo, Epiduo Forte, Twyneo)

What not to mix with benzoyl peroxide? ›

Unless your doctor tells you otherwise, it is especially important to avoid using the following skin products on the same area as benzoyl peroxide: Any other topical acne product or skin product containing a peeling agent (eg, resorcinol, salicylic acid, sulfur, or tretinoin);

Can I buy benzoyl peroxide over the counter? ›

Many popular skincare brands also make products that contain benzoyl peroxide, but at a lower strength. These are available to buy in pharmacies, supermarkets and shops.

How long does benzoyl peroxide take to work? ›

How long you'll need to use it for depends on how quickly your condition improves. Benzoyl peroxide will usually start to work within 4 weeks, but once your acne is under control you may want to keep using it to stop your acne coming back.

Which form of benzoyl peroxide is best? ›

When selecting a benzoyl peroxide product, you may want to start with a 2.5 percent concentration, as it causes less drying and irritation, and then move to a 5 percent concentration if you see minimal results after six weeks.

Do dermatologists recommend PanOxyl? ›

Crown Laboratories' best-selling acne wash, PanOxyl, has been named the No. 1 dermatologist recommended Benzoyl Peroxide brand, per a ProVoice survey by IQVIA, conducted late 2023.

What cancels out benzoyl peroxide? ›

Retinol and Benzoyl Peroxide

It is useless to use benzoyl peroxide, which is usually used to treat acne, and retinol together, says Paviol. The ingredients can cancel the positive effects of each other out and leave skin extremely dry and irritated.

What is the best combo for benzoyl peroxide? ›

Begin with benzoyl peroxide and adapalene.

If you're not sure which acne product to buy, start with one that contains benzoyl peroxide, adapalene or both. Either one is effective and usually well tolerated. Some studies show that they are more effective when combined. Give it a few days before expecting to see results.

Which is better, glycolic acid or benzoyl peroxide? ›

Glycolic acid can also affect the outer skin barrier, helping it retain moisture instead of drying your skin out. This is an advantage for acne-prone skin, because many other topical anti-acne agents, like salicylic acid and benzoyl peroxide, are drying.

What percentage of benzoyl peroxide is best? ›

It is typically placed over the affected areas in gel or cream form, in concentrations beginning at 2.5% and increasing through the usually effective 5% to up to 10%. Research suggests that 5% and 10% concentrations are not significantly more effective than 2.5%, and 2.5% is usually better tolerated.

What is the strongest acne medication? ›

Isotretinoin: This is a potent medicine that attacks all four causes of acne—bacteria, clogged pores, excess oil, and inflammation (redness and swelling). About 85% of patients see permanent clearing after one course of isotretinoin.

What is the best face wash with benzoyl peroxide? ›

Selected. Our top picks
  • Best cleanser. Cerave Acne Foaming Cream Cleanser. $12.67. $17.99. Amazon. Learn more.
  • Best body wash. PanOxyl 10% Benzoyl Peroxide Body Wash. $undefined. $9.77. Amazon. Learn more.
  • Best spot treatment. La Roche-Posay Effaclar Duo Acne Spot Treatment. $undefined. $35.99. Amazon. Learn more.
Jun 7, 2024

Is it better to use benzoyl peroxide at night or morning? ›

Acne in adolescents and young adults was effectively reduced with morning low-dose benzoyl peroxide (BPO) treatment combined with an evening stabilized cosmetic retinol, according to study findings published in the Journal of Drugs in Dermatology.

Should you moisturize after benzoyl peroxide? ›

When using topical benzoyl peroxide, moisturize first. Let in soak in, then apply the benzoyl peroxide. This helps buffer the medication and compensates for its drying effects. With benzoyl peroxide cleansers or washes, first cleanse, then apply moisturizer while your skin is still damp.

Is there benzoyl peroxide in CeraVe? ›

CeraVe Acne Foaming Cream Cleanser is formulated to thoroughly dissolve dirt and excess oil, while clearing acne with 4% benzoyl peroxide. CeraVe Acne Foaming Cream Cleanser combines the acne-fighting ability of benzoyl peroxide with three essential ceramides to support a healthy skin barrier.

Do you need a prescription for 10% benzoyl peroxide? ›

Benzoyl peroxide products that you can buy without a prescription are available in strengths from 2.5% to 10%. Studies show that lower strength products are as effective as higher strength preparations. Consider starting with a lower strength (2.5%) water-based product to lower the risk of side effects.

Can you get benzoyl peroxide on prescription? ›

There are many benzoyl peroxide products available. Many can be purchased without a prescription. Some products (such as creams, cleansers, foam, or lotions) may require a prescription. Consult your doctor or pharmacist on the choice of the product that is best for you.

Will a dermatologist get rid of my acne? ›

With today's acne treatments and a dermatologist's expertise, virtually every case of acne can be cleared. A dermatologist can tailor a treatment plan to your unique needs.

What skin conditions does benzoyl peroxide treat? ›

Benzoyl peroxide topical is used to treat acne and may be used for other skin conditions as determined by your doctor. Epsolay® topical cream is used to treat inflammatory lesions (pimples and red bumps) caused by rosacea.

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